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Thus, in this study our initial goal was to identify LOX-metabolites (particularly 4-OXO-DHA) in rats administered DHA by oral gavage twice weekly until termination of the bioassay ( cf

Exercise, which is known to improve menopausal metabolic health, increases MOTS-C levels by 11.9 times in muscle tissue, suggesting that some of the metabolic benefits of exercise during menopause may be mediated through MOTS-C pathways

Nakamichi et al

The FPI model has been established as one of the most widely used methods of inducing injury and has been used in a variety of animal species including rabbit (Hrtl et al., 1997), dog and sheep (Millen et al., 1985), cat (Povlishock et al., 1983), pig (Thompson et al., 2005)