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Description
doi: 10.1021/acschemneuro.6b00175
1 Years earlier, in the search for compounds that are selectively lethal to RAS-mutated tumor cells, researchers already identified two structurally independent small molecules named erastin and RSL3 that were able to induce a unique form of cell death
Arginine stimulates the pituitary gland to secrete growth hormone by suppressing an inhibitory hormone (somatostatin)
Since the cellular synthesis of glutathione is ATP-dependent, decreased ETC activity also undermines glutathione synthesis, further exacerbating oxidative stress in a vicious cycle [8]
