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This is because placing a new patch in the same place as the old one may irritate your skin
[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Anastasiou D, et al
2000 Aug;16(2):253-62
For OA, employing local intra-articular administration is expected to significantly reduce systemic exposure and related immune reactions, thus being considered a more realistic clinical translation pathway (Lin et al., 2024
