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This report describes the structure-based discovery of inhibitors of the FAK FAT domain utilizing the native sequence of the alpha-helical LD2 motif of paxillin (conserved sequence: SELDXLLXXL)
Its active component, EGb 761, has shown potential in enhancing memory, promoting neurogenesis, and improving brain plasticity in animal models
Time shows hours of incubation in 38.4 O C
