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For example, elevated ROS levels caused by copper overload disrupt mitochondrial membrane permeability, leading to a decrease in mitochondrial membrane potential, which in turn triggers the release of apoptotic proteins, ultimately leading to apoptosis in mouse cells (Liu et al., 2020a)

(2009) Critical evaluation of toxic versus beneficial effects of methylglyoxal, Biochemistry (Moscow) , 74 , 1059-1069, Krl, M., and Kepinska, M

Our findings show that while previous investigations of this issue may have been confounded by between-subject effects, objective sleep quality is indeed reflected in subjective sleep ratings
