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it can interfere with antigen presentation, prevent T-cell activation, inhibit toll-like receptor signalling, and reduce the production of inflammatory cytokines by T-cells and B-cells [40]

38 In individuals with prominent dehydration (eg, athletes, malnourished individuals, or members of vulnerable populations), care must be taken to ensure adequate electrolyte-rich solutions, particularly high-salt formulations

Ongoing clinical research is required to clarify long-term effects, optimal dosing, and durability of responses