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While the canonical IL-4/STAT6 pathway is the well-established initiator of the M2 transcriptional program, our findings suggest that direct activation of PKA in M1 macrophages (using Db-cAMP) was sufficient to significantly enhance efferocytosis
Three reasons can cause deficiency, inadequate intake, inadequate bioavailability, or malabsorption
e071725e071725, www.bmj.com/content/383/bmj-2022-071725, Dangour, Alan D, et al
