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Weatherall (2001) Phenotypegenotype relationships in monogenic disease: lessons from the thalassaemias Nature Reviews Genetics 2:245255 Kyrri AR, Kalogerou E, Loizidou D, Ioannou C, Makariou C, Kythreotis L, Phylactides M, Kountouris P, Angastiniotis M, Modell B, Kleanthous M.(2013)The changing epidemiology of -thalassemia in the Greek-Cypriot population

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Each batch is produced under conditions designed to minimize variance in purity and composition so your data reflects the biology youre studying, not inconsistencies in your reagents