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For oral administration, mild gastrointestinal symptoms such as dyspepsia, nausea, vomiting, or diarrhea are the most common adverse effects [16,17]

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Furthermore, numerous studies indicate that reactive oxygen species (ROS) may need to interact with other intracellular signals, such as inflammatory factors or changes in ion channels, to effectively induce the assembly and activation of the NLRP3 inflammasome [288]

The effectiveness and cost-effectiveness of methods of storing donated kidneys from deceased donors: a systematic review and economic model