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Preclinical data demonstrate a restoration of intestinal barrier function upon stimulation with FXR agonists, e.g., obeticholic acid (128)

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The trial enrolled 300 obese subjects (BMI 27-35 kg/m) across multiple centers and randomized them to AOD-9604 (3 mg subcutaneous injection once or twice daily) or placebo for 12 weeks

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This peptide binds to ghrelin receptors, increasing the production of growth hormone, which in turn boosts muscle growth and repair

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10 days 1 vial About 10 daily draws at the example titration

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