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Variants in genes such as FTO (rs9939609), MC4R (rs17782313), and other lipid-metabolism loci may influence how efficiently your body mobilizes fat and responds to metabolic interventions

Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells

This contrasting result by sex might be due to immune system variation, as it is known that women have a stronger humoral/innate immune defence than men (144, 145), or, it could be attributable to a different microbiome composition (146)

WangLEvattMLMaldonadoLGPerryWRRitchieJCBeechamGWet al