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9a), Arbutin, which has a smaller molecular weight, tends to chelate with copper ions, interacting with H84, V282, and F263, with the hydroxyphenyl group directed towards the metal site

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By protecting neurons and supporting brain function, EGCG helps preserve cognitive abilities and may reduce the risk of conditions such as Alzheimers and Parkinsons disease

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Additionally, Apolipoprotein E/endothelial nitric oxide synthase double-knockout mice manifest an accelerated progression of atherosclerosis [81]

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[DOI] [PubMed] [Google Scholar] 373.Stamler JS, Meissner G

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