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9a), Arbutin, which has a smaller molecular weight, tends to chelate with copper ions, interacting with H84, V282, and F263, with the hydroxyphenyl group directed towards the metal site

By protecting neurons and supporting brain function, EGCG helps preserve cognitive abilities and may reduce the risk of conditions such as Alzheimers and Parkinsons disease

Additionally, Apolipoprotein E/endothelial nitric oxide synthase double-knockout mice manifest an accelerated progression of atherosclerosis [81]

[DOI] [PubMed] [Google Scholar] 373.Stamler JS, Meissner G