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Its circadian and melatonin-restoring effects are biologically coherent and supported by primate and human observational data

doi: 10.1172/JCI84427 80 CopelandBTShallalHShenCPientaKJFossCAPomperMG

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Maintaining cellular NAD supports mitochondrial function, stress resilience, and metabolic flexibilitykey mechanisms linking NNMT inhibition to improved energy balance (Kannt & Pfenninger, Frontiers in Physiology )
