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In another experiment, mice with cAtg3-KO-induced cardiac dysfunction were treated with 5-amino-1-MQ

N800 decreased the hepatic gene expressions of lipid transporter, lipid synthesis, and interferred -oxidation, leading to lipid accumulation and increasing Cyp2E1 expression, and finally, decreased ATP production

As already discussed above, at the post-transcriptional level, an important role in the regulation of the KEAP1-NRF2 system is played by miRNAs