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About GHK-Cu GHK-Cu (Glycyl-L-Histidyl-L-Lysine copper complex) is a naturally occurring tripeptide-copper complex first isolated from human plasma

Site-directed mutagenesis experiments show that cysteine-553 in human GLCLC is involved in heterodimer formation between the catalytically active GLCLC and the auxiliary, activity-enhancing GLCLR unit, which likely occurs through a disulfide bond [139]

The hypothesis was first introduced by Panksepp, who proposed that morphine could play a role in the development of ASD (Panksepp 1979)