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Neurodevelopmental manifestations of mitochondrial disease

Figure 1 Ferroptosis, a recently identified form of programmed cell death, is characterized by elevated levels of reactive oxygen species (ROS) and iron-dependent lipid peroxidation ( + to Fe + occurs after cellular iron uptake through transferrin receptor 1 (TFR1)

Although structurally similar to other ZNT family members that transport Zn, ZNT10 also functions as a Mn exporter (Nishito et al., 2016
