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PPAR/PGC1 signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders

The intestine has a high rate of energy utilization because the portal-drained viscera (PDV) (i.e., intestines, pancreas, spleen, and stomach), which contribute less than 5% of body weight (BW), account for approximately 30% of the whole-body energy expenditure and most of the energy that is utilized by the intestine 11,12

The regulatory network of iron homeostasis, lipid metabolism, amino acid metabolism, and antioxidant pathways provides new ideas for diagnosing and treating human diseases

10.3389/fimmu.2019.00155 [DOI] [PMC free article] [PubMed] [Google Scholar] Lin C
