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The pathogenic processes involved are multifactorial, encompassing direct impacts on the host and cooperative interactions with indigenous commensal microbiota that can lead to immune dysregulation
407 Selecting potential subgroups for chemotherapy de-escalation still needs further validation

Bowman, S

Concluding Remarks The multilayered functional interactions of the mTOR signaling pathways and the process of autophagy are deciphered to a great extent at the cellular level, but we still have an incomplete understanding of their integration at the physiopathological level
