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Protocol Initiation: Treatment begins with conservative dosing that is gradually optimized based on symptom response and lab results

10.1161/CIRCULATIONAHA.106.638460 [DOI] [PubMed] [Google Scholar] Cardenas-Rodriguez N., Huerta-Gertrudis B., Rivera Espinosa L., Montesinos-Correa H., Bandala C., Carmona-Aparicio L., et al

These findings confirm that impairment of the blood-brain barrier and microglial, endothelial cell, ATPase, and astrocyte function exacerbate MDD
