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10.1016/j.cell.2017.03.014 26 Prakash BabuN.PaolaM.Hamers AnoukA

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In the previous study, teicoplanin (TIL) treatment significantly upregulated the relative hepatic expression of HSP70 and NF-B mRNAs and blocked Nrf2/HO-1 mediated responses, indicating that TIL could induce oxidative stress and hepatotoxicity by blocking Nrf2 mediated defense responses and increasing NF-B signaling pathways

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