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At the end of the treatment period, the whole aortas were excised and the atherosclerotic plaque development was evaluated via ORO staining of the aortic arch

J., Barnes, P

Sasaki K, Jabbour EJ, Ravandi F, Konopleva M, Borthakur G , Wierda WG, Daver N, Takahashi K, Naqvi K, DiNardo C, Montalban-Bravo G, Kanagal-Shamanna R, Issa G, Jain P, Skinner J, Rios MB, Pierce S, Soltysiak KA, Sato J, Garcia-Manero G, Cortes JE

Within the TME, functionally altered SWI/SNF chromatin remodeling complexes cooperate with transcription factors including BATF and Foxp3 to reprogram the gene expression landscape of TI-Treg cells, thereby enhancing their immunosuppressive capacity