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Some microbial siderophores, low-molecular-weight iron chelating agents, sequester copper extracellularly and protect bacteria by minimizing intracellular copper penetration

This suggests a positive impact on immune function during cancer treatment [97,98]

Repair may be indicated by decreased levels of 7,8-dihydropterin and activation of steroid hormone biosynthesis

Metabolomics data further show coordinated rhythmic shifts in amino acids, B-vitamins, and lipid species across phases, which may reflect windows of greater metabolic vulnerability in which nutritional inadequacy, low energy availability, or high training loads may more readily precipitate symptoms or performance decrements [3]