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Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

While the present study cannot distinguish between these mechanisms, the consistency of the finding and its sensitivity to dietary intervention suggest that coumarin may represent a diet-responsive marker of metabolic dysregulation in this population

Tang, X., Liu, J., Dong, W., Li, P., Li, L., Lin, C., Zheng, Y., Hou, J., Li, D

doi:10.1016/j.cbpc.2018.09.003
