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Description
The ferroptosis inducer erastin irreversibly inhibits system x- and synergizes with cisplatin to increase cisplatins cytotoxicity in cancer cells
185 Besides, other MTHFD2 inhibitors have been reported, including DS18561882 and LY345899 in a substrate-based manner, and treatments based on them decrease cellular NADPH/NADP + ratio, increase cellular ROS levels, and impair tumorigenesis and metastasis
Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis
2021KJ121)
