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144 Based on estimates, under physiological conditions, one-third of the HSA exists as disulfides mixed with cysteine, homocysteine, or glutathione (HSA-S-S-R), whereas the rest of the HSA is in a reduced form with a free thiol in the Cys-34 residue (HSA-SH)

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Maternal nutrition can modulate gene expression through epigenetic mechanisms, methyl-donor micronutrients of one-carbon metabolism (folic acid, choline, and vitamins B6 and B12) are essential in many physiological pathways and processes, including DNA methylation (46)

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