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The loading phase is critical for establishing circulating levels of TB-500

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Since many isoforms of PKC are also activated by increases in intracellular Ca 2+ , both these pathways can also converge on each other to signal through the same secondary effector

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No clinical signs of toxicity were observed when a dose of 5 mg/kg was administered for 15 days

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The protocol is derived from component-level research and practitioner use

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