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The pronounced anti-aging effect of MSD-37 related to the IR extract could be linked to its higher polyphenolic concentration (151 mg GAE/mL) compared to MSD-21-IR (133.4 mg GAE/mL) and MSD-24-IR (124.2 mg GAE/mL), suggesting that increased polyphenolic content may contribute to its biological activity

2.13.1.6 SAMP8 mice SAMP8 (Senescence-Accelerated Mouse Prone 8) mice, a spontaneous AD model, exhibit age-related cognitive decline, oxidative damage, and impaired BBB function

Mitophagy in cardiomyocytes and in platelets: a major mechanism of cardioprotection against ischemia/reperfusion injury