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By calculating both the oxidation rates of OxyR and Tpx1 by peroxides, and their reduction rates by the cellular redoxin systems, we propose that, while Tpx1 is a sensor and an efficient H 2 O 2 scavenger because it displays fast oxidation and reduction rates, OxyR is strictly a H 2 O 2 sensor, since its reduction kinetics are significantly slower than its oxidation by peroxides, and therefore, it remains oxidized long enough to execute its transcriptional role

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However, AMPK also suppresses the fatty acid transporter CD36, limiting fatty acid uptake and oxidation and thus aggravating metabolic imbalance

Rather than passively existing in natural or unnatural growth environments, microorganisms establish physiological and metabolic interactions and adapt to changes in their living environments by regulating their metabolism, particularly through SM production (Singh and Lee, 2018)