glutathione and diabetes pdf The Role of Its Precursors in Type 2 Glutathione at the Crossroads of

Reduced cardiolipin content, alterations in its acyl chain composition and/or increased cardiolipin peroxidation have been linked to mitochondrial dysfunction in multiple tissues during aging and in neuropathological disorders (Monteiro-Cardoso et al., 2015)

Additionally, zinc acts as a cofactor for superoxide dismutase (Cu/Zn SOD) and regulates the expression of metallothioneins, which scavenge ROS (367)

[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Shim S.-M., Yoo S.-H., Ra C.-S., Kim Y.-K., Chung J.-O., Lee S.-J

Their actions are involved in glutathione production, scavenging of potentially harmful reactive free radicals, and primarily phase II liver detoxification