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CYTOSOLIC AND MITOCHONDRIAL ONE-CARBON METABOLISM GENERATES NADPH One-carbon metabolism integrates the amino acids serine and glycine into the folate and methionine cycles that participate in many diverse biological outputs, including nucleotide synthesis (see Chandel 2020c) and methylation reactions involved in epigenetics (see Chandel 2020d)

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This dual action of NAC, both in protecting the BBB and in reducing inflammation, makes it a promising candidate for neuroprotective therapy

The samples clustered tightly within their groups indicating high reproducibility