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These effects are attributed to a variety of phytochemicalsincluding quercetin, apigenin, and lupeolknown to modulate oxidative stress and vascular function

Hypomethylation of the promoter regions of tumor-promoting genes such as uPA and matrix metalloproteinase-2 ( MMP-2 ) have been associated with tumor growth in prostate cancer PC-3 cell line, which can be reverted by SAMe treatment [212]

doi: 10.1016/S0981-9428(00)01188-8 21 Diaz VivancosP.DongY.ZieglerK.MarkovicJ.PallardF

doi: 10.3891/acta.chem.scand.23-3290
