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Description
Bilirubin is prevented from returning to the plasma by binding with ligandin in liver cells
Furthermore, urothelium from individuals with IC has demonstrated reduced cell proliferation and increased cell permeability (Fiehn and Kim, 2014)
This underscores the persistent significant gaps in translating pathophysiological understanding into consistently effective, personalized therapies across healthcare systems
Both forms lead to chronic anemia, which stimulates increased erythropoietin production
