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In contrast, under oxidative stress NRF2 dissociates from KEAP1 and translocates to the nucleus, where it activates the downstream expression of antioxidative response element (ARE)-containing target genes, many of which have been shown to play a role in defending against ferroptosis [65, 66]
Bank Foundation United Technologies USAA Group Joseph Vaghi Mary Vaghi Plutarco B
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doi:10.1016/s1522-8649(11)50016-2
