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Its mechanism suggests potential benefit, but without validated dosing protocols or safety data in ischemic models, using it as a primary intervention introduces unquantified risk and reduces study reproducibility

TheofilisPSagrisMOikonomouEAntonopoulosASSiasosGTsioufisCet alInflammatory mechanisms contributing to endothelial dysfunction

I think we can safely say the overwhelming answer would be (b)

Mean age 73.81 years (SD: 12.80), Median ASPECTS 7 (IQR: 6-7)
