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On the other hand, (ii) the first assessment of the analgesia in the absence of morphine (time "0"), the application of saline was administered 30 min in advance (time "-30 min"), the application of haloperidol or gastric pentadecapeptide BPC 157 or naloxone or saline 20 min in advance (time "-20 min"), and the application of saline 10 min in advance (time "-10 min")

Moreover, as non-thiol antioxidants (vitamins C and E) did not antagonize BSO+L-PAM cytotoxicity, it is likely that NAC and STS act to directly replace GSH as an absorbent of the highly reactive L-PAM

PMID 2137911 Subcutaneous injection-site pharmacokinetics FDA review