mitochondrial glutathione reductase Frontiers Glutathione Depletion in Mitochondrial Diseases

Description

& Double, K

In the presence of guide RNA (gRNA) and Cas9 endonuclease, the gRNA directs the Cas9 endonucleases to cleave the DNA at a specific location, creating indels in the gene, inducing a frameshift mutation, generating a constitutive knockout

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