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Other reported functions include cytosolic redox sensing and involvement in the mitochondrial oxidative folding machinery (Alvarez-Paggi et al

and B) because if active proteases are found in the same time and place as not-yet-converted PrP C , why dont they just digest it

Sasaki K, O'Brien S, Thomas D, Khouri M, Yilmaz M, Garcia-Manero G, Ravandi F, Borthakur G , Garris R, Gachimova E, DiNardo C, Pemmaraju N, Cortes J, Kantarjian H, Jabbour E

Oligodendrocytes also store large quantities of iron within ferritin [104, 105], but have low levels of the important reactive oxygen species (ROS) reducing agent glutathione (GSH) [106], which suggests that oligodendrocytes may be especially vulnerable to changes in metabolic rates and ROS