l carnitin muskelaufbau L-Carnitin Catalog - Reader - Peter

Primary Deficiency Secondary Deficiency Hemodialysis Support Metabolic Disorders

Primary carnitine deficiency (PCD) is an autosomal recessive disorder characterized by a lack of plasma membrane carnitine transport owing to a shortcoming in the OCTN2 carnitine transporter

Atrogin-1 and MuRF1 expression in skeletal muscle is increased by cytokines or reactive oxygen species (ROS) and constitutive activation of NF-kB in animal models, leading to muscle loss and atrophy (Ringseis et al., 2013)

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