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Description
Another barrier in the current landscape of the field is the potential for off-target effects using the mechanisms described here
10.1016/j.plipres.2020.101071 35 Falik-BorensteinZ
[117] reported low concentrations of free carnitine and acylcarnitines (glutarylcarnitine, octylcarnitine, and carnosylcarnitine) in children with ASD in dry blood spots in comparison to healthy children

The accumulation of Fe 2+ leads to the Fenton reaction between Fe 2+ and PUFAs-O-OH, which generates ROS, accelerates lipid peroxidation, and induces ferroptosis
