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The elevated macrocytic index and the dietary history were the diagnostic clues in this patient

Olde Damink SW, Jalan R, Redhead DN, et al
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A subsequent isolation and amino acid sequence determination of two homogeneous polypeptides from purified non-suppressible insulin-like activity factors (158160) established the current designation of these molecules as insulin-like growth factors (IGFs) 1 and 2 (161)
