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However, if certain alveolar regions become atelectatic, homogenous ventilation is significantly impaired

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Although several genes such as Fgf21 (Figure 2C), Pdk4 , and Acot2 showed a modest suppression in their induction upon the loss of Atgl in Cpt2 L/ mice, most genes in DKO mice resembled the response of Cpt2 L/ mice (Figure 4A)

Participants weighing 45 kg or less received 1350 mg/day of Idebenone with meals, whilst those weighing 45 kg or more received 2,250 mg/day Idebenone with meals