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In line with this issue, the elevated levels of pro-inflammatory cytokines, including interleukin-1 beta (IL-1), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-), have been observed in diabetic models [11]

At the second visit, a dermatologist recorded melanoma risk factors, performed a whole-body examination, and performed a biopsy of lesions suggestive of melanoma for evaluation by a central dermatopathology laboratory