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Journal of the American Heart Association

Additionally, a grade 2b study in 2012 with 80 participants also showed that daily administration of 1 g LC for 7 weeks could achieve similar effects as the antidepressant fluoxetine, with statistically significant improvements in various measures of depression and anxiety [36]

37 They are used when 2 ligands and SNRIs are ineffective or contraindicated

The evidence for symptomatic treatments in amyotrophic lateral sclerosis