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Description
Administration of spironolactone, a selective MR antagonist, counteracted stress-induced mGlu2 suppression and the related development of depressive-like behavior, implicating rapid action of glucocorticoids via a receptor that is known to modulate glutamate release [20]

These include a history of infection, the use of certain drugs, especially TNF- inhibitors, smoking, alcohol, and stress (195, 199)

Sleep Hygiene Most people with fibromyalgia have sleep difficulties

& Guo, L.-M