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2012;22(6):758762 [DOI] [PubMed] [Google Scholar] 77

Metabolic clustering analysis as a strategy for compound selection in the drug discovery pipeline for Leishmaniasis

[6,7] In addition, treatments with biologics can be costly and increase the risk of systemic immune suppression

Research indicates that acute stress triggers the activation of AgRP neurons, leading to the expression of neuropeptide Y (NPY), which then promotes presynaptic inhibition of GABAergic neurons expressing NPY1R and activates CRH neurons in the paraventricular nucleus (PVN) of the hypothalamus, thereby stimulating the HPA axis and increasing circulating CORT levels