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Carboplatin in the treatment of Ewing sarcoma: results of the first Brazilian collaborative study group for Ewing sarcoma family tumors-EWING1

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2.6 Investigating the mechanism of drug interaction by proteomic and phosphoproteomic analysis To elucidate the synergistic mechanism of our double and triple drug combinations, we examined the proteomics and phosphoproteomics changes in MNA Be(2)-C cells treated with DPI+/-MitoQ+/-Vin for 24 hours by mass spectrometry (MS)