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Modulation of mTOR signalling as a strategy for the treatment of Pompe disease
(2021) in a randomized, triple-blind, placebo-controlled study evaluated the efficacy of freshwater marine collagen for 12 weeks on skin attributes in women 4560 years of age in Canada [36]
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This study also found that elevated GPX4 expression promoted PHC activity, and silenced GPX4 expression achieved contrary results, again validating the regulatory role of GPX4 on PHC progression
