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Description
Patients were asked to record a pain score using a 10-cm visual analog scale and procedure tolerability
Facchinetti, F., Cavalli, P., Copp, A
Shinzhen, 2006)
Because ipamorelin and GHRH analogs act through separate receptor pathways (GHS-R1a versus the GHRH receptor), preclinical research has investigated the two compound classes together, hypothesizing that dual-pathway stimulation may produce additive or synergistic effects on GH release compared with either pathway alone a design that leverages the cAMP/calcium signaling distinction described above
