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In fact, SAG is an active antioxidant in all tissues and supports immune function
To determine the effects of stimulating TCA cycle activity, we treated hepatocytes with dichloroacetate, which stimulates substrate entry into the TCA cycle by inhibiting PDKs (Constantin-Teodosiu, Simpson, & Greenhaff, 1999
That would help patients with treatment-resistant insomnia, patients in structured opioid withdrawal programs, and potentially patients with narcolepsy who have not responded to standard medications
doi: 10.1016/j.ejphar.2005.11.016 63 WinklerGNagybeganyiBPEOryIPorochnavecMKemplerP
