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Lim, J.-e et al

Peroxisomemitochondria axis For the peroxisomemitochondria axis, the rationale is that peroxisomal -oxidation is a major H 2 O 2 source (via acyl-CoA oxidases and other flavoproteins) and peroxiporins allow H 2 O 2 to exit the organelle and coordinate with cytosolic and mitochondrial pathwaysso when flux outstrips buffering, lipid-peroxide pressure rises and spills into neighbouring compartments (Lismont et al

This leads to the assumption that these individuals also have a lower risk of many chronic diseases, as these parameters contribute to their development

Long-term low-dose colchicine can also be used for flare prophylaxis